Ecocert Certified - Greater than 98% Natural & Plant-based Ingredients | EWG Verified - Zero Toxins, Pregnancy & Baby Safe
Wound-Healing Test
No Preview
A wound-healing assay, also known as a Boyden chamber assay or scratch assay, helps us to decode the wound-healing effect of our products. It involves creating a gap or "wound" in a layer of cultured cells and observing how quickly and effectively the cells migrate to close/heal the gap.
We test our formulations on dermal fibroblast cell lines to check their wound-healing effect.
What Are Dermal Fibroblasts & Why We Use It?
No Preview
Dermal fibroblasts are the predominant cells present in the dermal extracellular matrix. They play an integral role in maintaining skin physiology and repair by producing collagen, elastin, and proteins like laminin & fibronectin. Dermal fibroblasts are an excellent tool for investigating the chemotactic property/wound healing of our products as they are less likely to replicate or differentiate in an in vivo (testing on a living organism) or in vitro (testing in a lab)environment.
How We Test The Wound-Healing Effect Of Our Products?
pattern
No Preview
Step 1
pattern

We introduce a suitable liquid medium to the test product, transfer it into a special plate, and finally place a Boyden chamber over the same....

Read more...
Step 2
pattern

Next, we introduce dermal fibroblasts cells into a liquid medium to support their growth & replication. These cells are then placed on top of the filter/porous membrane.

Step 3
pattern

This set-up is left unattended for one day under suitable lab conditions.

Step 4
pattern

Due to the chemotactic (chemical signals to attract cells) property of our test product, the cells travel across the membrane into the test solution....

Read more...
Step 5
pattern

On day 2, we stain the dermal fibroblasts migrated under the membrane using a suitable dye and track their number through a spectrophotometer.

What's The Final Result?
For a product to be considered chemotactic/healing, the test solution should have higher number of dermal fibroblasts than solutions without the test product (untreated control). At Areoveda, the tested products reveal similar results!
Pick From Our Range Of Tested Wound-Healing Test Products Now
pattern
Blog
pattern
Journal1
Post By : Shaheen Naser
6 Skin Care Tips For New Moms & Moms-To-Be
Are you always waking up to panda-looking under eyes and dry, peeling skin? Do red, angry bumps stare back at you whenever you look in the mirror? Or, is it the uneven tone and dark, patchy skin that gets your panic mode on?
May 08, 2024
Journal1
Post By : Umme Sadiya Qamar
Post-Pregnancy Dark Circles Under Eyes - Causes & Tips To Overcome Them
Dark circles under the eyes are also known as periorbital dark circles. They are usually characterised by darker under-eye skin tone compared to the surrounding areas of the facial skin. The under-eye skin skin colour of a person is strongly influenced by inherent factors such as ethnicity and genetics.
May 08, 2024
Journal1
Post By : Shaheen Naser
Stretch Marks During Pregnancy: Everything You Should Know
Medically termed as striae distensae, stretch marks are pink, red or purple colored skin lesions that occur as a result of changing hormone levels in the human body. They occur in 90% of women and are one of the leading cosmetic concerns worldwide. Pregnancy, weight gain or loss, puberty, and muscle building are all obse
May 08, 2024